I know that this is a bit old, but I hope that it is OK to add something to it...

I have been on Wellbutrin for almost 10 years now. I previously had troubles with very serious to moderately serious side effects with all other antidepressants that I have tried, and have had next to no side effects with this medication. I am on 300mg XL.

I have recently been going through an extremely intense period of therapy and the emotional intensity has been off the charts, which actually makes things difficult to really process. According to the psychiatrist with whom I have recently started working, while Wellbutrin works very well as an antidepressant, it does very little to nothing with anxiety or emotional states. It seems that the SSRIs are better at doing this. She has me trying a very, very small dose of Zoloft (12.5 mg) in addition to the Wellbutrin, in an attempt to tone down the emotional intensity just enough so that I can more easily do the work that I need to do in session. We are hoping that because the dose is so tiny, I will be able to avoid any bad side effects.

Just recently, my husband also started on Wellbutrin, and we were warned that it can sometimes cause irritability, especially at the beginning.